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انتهت بتاريخ ١ أبريل ٢٠٢٦
Senior Scientist I, Pipeline Development & SAR Optimization
وصف الوظيفة
At AbbVie, we are dedicated to solving some of the world’s most complex and serious diseases. As a Senior Scientist in our siRNA group, you will be part of an innovative team focused on advancing RNA-based therapies that have the potential to revolutionize patient care. This role involves designing and executing innovative experimental approaches to address key scientific challenges related to oligonucleotide therapeutics.
المسؤوليات
- Lead research efforts within a cross-functional team to advance new therapeutic targets for siRNA-based pipeline development
- Design and execute in vitro and in vivo proof-of-concept studies to evaluate siRNA library and characterize lead compounds
- Design and execute structure-activity-relationship (SAR) studies for lead optimization
- Provide scientific leadership and expertise in candidate nomination and pipeline development
- Work independently and maintain a high level of productivity in the laboratory
- Analyze and interpret multidisciplinary data to generate actionable conclusions
- Collaborate and effectively communicate results with key stakeholders
- Contribute as a primary author to scientific publications, presentations, and patent applications
- Mentor and support junior scientists within the team
المؤهلات
- BS, MS, or PhD in chemistry, molecular biology, biochemistry, or related field with typically 10+ years (BS), 8+ years (MS), or 0-3 years (PhD) of experience
- Demonstrated expertise in siRNA therapeutics, including library design, screening and characterization of SAR
- Demonstrated expertise for siRNA candidate nomination and pipeline development
- Extensive hands-on experience and techniques for molecular and RNA biology
- Strong written and verbal communication skills